Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Short-Term Effects of Olive Oil and Flaxseed Oil for the Treatment of Constipation in Hemodialysis Patients

Full text
Author(s):
Ramos, Christiane Ishikawa [1] ; Andrade de Lima, Aline Fatima [2] ; Grilli, Daniela Gimenes [2] ; Cuppari, Lilian [1, 2]
Total Authors: 4
Affiliation:
[1] Univ Fed Sao Paulo, Grad Program Nutr, BR-04039000 Sao Paulo - Brazil
[2] Univ Fed Sao Paulo, Div Nephrol, Dept Med, BR-04039000 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: JOURNAL OF RENAL NUTRITION; v. 25, n. 1, p. 50-56, JAN 2015.
Web of Science Citations: 8
Abstract

Objectives: To evaluate the effects of olive oil and flaxseed oil compared with mineral oil for the treatment of constipation in patients undergoing hemodialysis. Methods: A 4-week, double-blind, randomized, and controlled trial was conducted. Fifty constipated patients (29% male, 51 +/- 12 years) diagnosed by the Rome III criteria were randomly assigned to receive mineral oil (control group; n 5 17), olive oil (n = 16), or flaxseed oil (n = 17). The initial oil dose was 4 mL/day, and adjustments during the follow-up could be made as needed. The impact of the intervention was assessed by the Rome III criteria scores. Results: The most frequent symptoms of constipation evaluated by the Roma III criteria at baseline were comparable among the groups and included ``incomplete evacuation{''} (92%), ``lumpy or hard stools,{''} (72%) and ``anorectal obstruction'' (70%). The Rome III score improved significantly in patients receiving mineral oil (10.5 +/- 5.0 to 4.1 +/- 4.0; P < .01), olive oil (10.3 +/- 4.2 to 3.2 +/- 3.8; P = .01), and flaxseed oil (9.6 +/- 4.2 to 6.0 +/- 5.1; P < .01), with no significant group-by-time interaction (P = .15). The scores of 5 from 6 constipation symptoms reduced similarly in the mineral oil and olive oil groups, whereas only the frequency of evacuation and the consistency of stools improved in the flaxseed oil group. Conclusions: We demonstrated that the daily use of olive oil or flaxseed oil was as effective as mineral oil in the treatment of constipation in patients undergoing hemodialysis. (C) 2015 by the National Kidney Foundation, Inc. All rights reserved. (AU)

FAPESP's process: 12/06605-9 - Effect of flaxssed and olive oils compared to mineral oil in the treatment of constipation in patients with chronic kidney disease on hemodialysis
Grantee:Christiane Ishikawa Ramos
Support Opportunities: Scholarships in Brazil - Master