CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Esporte from Universidade de São Paulo (2005) and doctorate at Nutrition from Universidade Federal de São Paulo (2010). Has experience in Immunology, focusing on Immunology, acting on the following subjects: inflamção, ácidos graxos, músculo esquelético and sensibilidade à insulina. (Source: Lattes Curriculum)
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Cancer has shown epidemic levels bringing considerable economic and social impact in modern society. Nowadays, cancer is the second cause of death in the world, with a high probability to become the principal cause of death in the next decade. Although several advances in the treatment, the life expectancy and quality of life of the patient can be affected by the chemotherapy. Our group …
The obesity is na epidemic condition in developed and development countries. The high consumption of fat acids in ocidental diet, and the sedentarism induced the body weight gain, and the accumulation of fat acids in depots of adipose tissue, and other organs, such as liver. This condition caused the low grade inflammation, condition that it is presented in the genesis of co-morbidates as…
Doxorubicin is an antibiotic of antracyclines family, that is the most to use in clinical practice, in treatment of solid tumours. However, this drug cause great cardiotoxicity. Moreover is common the patients development several fatigue and asthenia, during the treatment. Recents works showed that others organs are still injured by doxorubicin treatment, as adipose tissue, skeletal muscl…
The immune system is responsible for the body's defense and repair process, for this, it recognizes its own molecules and those that are not of the individual. In principle, the immune system is divided into innate and adaptive, being differentiated by the level of specificity of the cell receptors present in each one. All this to maintain the homeostasis and integrity of the body. With a…
Aging is characterized by a gradual decline in numerous physiological processes, including changes in the immune system, which are collectively called immunosenescence and the circadian rhythm that show significant changes related to age. The relationships between clock genes, aging and immunosenescence are not well understood. The role of clock genes in innate immunity is evident, but fe…
Cancer is the disorderly and aggressive growth of cells, existing more than 100 types of cancer. This complex group of diseases is the second leading cause of death worldwide, second only to cardiovascular disease. Just in 2018, Brazil recorded a total of 224,712 deaths from cancer, 117,477 men and 107,235 women, of whom 17,572 (16.4%) were due to some type of breast cancer. It is estimat…
Tumor cells have characteristics of exaggerated proliferation, angiogenesis, growth, invasion and metastasis, and even resistance to death. Like many other diseases, cancer involves genetic and environmental risk factors. Unhealthy diet, low level of physical activity, alcohol consumption, exposure to radiation and smoking are among the main factors causing the disease related to the envi…
Cancer is the second most deadly disease in the world. Most of the treatments against this morbidity involve the use of chemotherapy, but despite the antiproliferative effects of this therapy, the toxicity is very great, leading to a decrease in the expectation and quality of life. The association of tumor to therapy often induces proteolysis, leading to decreased ability of the individua…
(Only some records are available in English at this moment)
Cancer is one of the main causes of death worldwide, and the leading type of cancer new cases in 2020 was breast cancer. Triple-negative breast cancer (TNBC), accounts for 10-15% of all breast cancers and is characterized by lack of estrogen, progesterone and human epidermal growth factor receptors expression. It is the most aggressive, and therefore therapies are more intricate. Immune c…
Introduction: Allogeneic hematopoietic stem cell transplantation (HCT) is one of the main treatments for hematological malignancies. HCT provides prolonged disease-free survival for many patients, but relapse remains the most frequent cause of death. Donor lymphocytes infusion (DLI) is used after HCT to treat or prevent disease relapse by boosting the graft versus tumor (GvT) effect, howe…
The Ca2+-calmodulin (Ca2+-CaM) dependent protein kinase kinase-2 (CaMKK2) is the core component of a signalling pathway in neurons that regulates appetite, mood and whole-body energy metabolism. We recently discovered that, in addition to being activated by Ca2+-CaM, CaMKK2 is also activated by fatty acid metabolites (palmitoyl -CoA). Emerging evidence indicates that fatty acids released …
Colorectal cancer compromises large bowel and rectum. Approximately 20% of patients with inflammatory bowel disease (IBD) develop colon cancer and this population has twofold increase in mortality. IBD is a chronic inflammatory condition of the gastrointestinal epithelium due to alterations in immune system reactivity. In colorectal colitis-associated tumors and in IBD, there is a disrupt…
(Only some records are available in English at this moment)
| 3 / 3 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 12 / 12 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 6 / 6 | Completed scholarships abroad |
| 24 / 24 | All research grants and scholarships |
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