CV Lattes
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ORCID
Universidade Estadual Paulista (UNESP). Campus de Araraquara. Faculdade de Ciências Farmacêuticas (FCFAR) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Farmácia from Universidade Metodista de Piracicaba (2002), master's at Pharmacy from Universidade Estadual Paulista Júlio de Mesquita Filho (2004) and doctorate at Pharmacy from Universidade Estadual Paulista Júlio de Mesquita Filho (2007). Has experience in Pharmacy, focusing on Pharmacotechnie, acting on the following subjects: estágio supervisionado, sistemas líquido-cristalinos, assessoria científica, cafeína and estabilidade físico-química. (Source: Lattes Curriculum)
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Candida albicans is the most prevalent yeast in vulvovaginal candidiasis (VVC) episodes. Currently, the available therapy for this infection involves the administration of drugs, however, several resistance cases has been observed. Due to these factors, the search for new sources of antifungal molecules, among them, the natural products derivatives is in expansion. The hypericin (HIP) is …
Candida albicans is the most prevalent yeast in vulvovaginal candidiasis (VVC) episodes. Currently, the available therapy for this infection involves the administration of drugs, however, several resistance cases has been observed. Due to these factors, the search for new sources of antifungal molecules, among them, the natural products derivatives is in expansion. The hypericin (HIP) is …
Current anticancer therapies often demonstrate reduced safety and efficacy, so the development of new therapeutic approaches to cancer has been the goal of much research. In this context, activation of the host immune system against tumor antigens has received special attention as it represents a significantly safer and more effective alternative than chemotherapy and other conventional c…
Cervical cancer, a malignant tumor that affects the lower part of the uterus, is the third most frequent tumor in women, caused mainly by persistent infection by some oncogenic types of Human Papillomavirus (HPV). Although diagnostic and preventive capacity has evolved in recent decades through HPV vaccines and Pap smears, cervical cancer is still very much a problem in the female populat…
(Only some records are available in English at this moment)
There remain several key challenges to existing for Colorectal Cancer (CRC) therapy by intravenous route, mainly associated to the targeted delivery of drugs in the colon and/or tumor region as well as the systemic side effects reduction. 5-fluorouracil (5-FU) is one of the first-line chemotherapeutic drugs in the CRC therapy; however, it has short plasma half-life, unstable absorption in…
Glioblastoma Multiforme (GBM) is the most incident and most aggressive neoplasm of the Central Nervous System (CNS). Temozolamide (TMZ), the drug of choice for the treatment of GBM, has clinical efficacy, but treatment with this drug is associated with the development of resistance in more advanced stages of the disease, in addition to the fact that TMZ has physical and chemical limitatio…
Prostate Cancer is the second cancer with the highest mortality in Brazil, affecting mainly men in old age. The recommended treatment varies according to the tumor stage, and it is possible to choose therapies alone or in combination. Among therapies, chemotherapeutic agents are widely used; however, the tumor may show resistance causing the efflux of drugs from the cell, in addition to g…
(Only some records are available in English at this moment)
Vulvovaginal candidiasis (VVC) is a disease that affects a large part of the female population, Brazil ranking third in number of incidences of VVC in the world. The symptoms of this disease are nonspecific and are related to inflammatory processes resulting from the infection. The treatment currently available corresponds to oral and topical forms of drugs in the azole class; however, an…
Systemic infections caused by fungi of the genus Candida, especially the new species such as C. auris, which are highly resistant to the main drugs available to the population, have been causing a serious global public health problem, especially in the nosocomial environment. Authorities around the world remain alert to the rapid progression of disease states attributed to this species du…
Aedes aegypti L. is an insect of great medical importance because it is the transmitter of several diseases that cause significant problems to public health worldwide, such as Dengue, ZiKa, Chikungunya and Malaria. The main ways to prevent infection with these viruses are the use of repellents and larvicidal agents that eliminate insect larvae. Medicinal plant derivatives have been used s…
(Only some records are available in English at this moment)
Vulvovaginal candidiasis currently represents a major public health challenge due to its high incidence and recurrences reports. These challenges may be due to host-related factors, such as compromised immune system, or pathogen-related factors, including resistance to antifungal agents, and making necessary to study new treatment alternatives, e.g., the use of natural origin substances s…
Helicobacter pylori is a microorganism that is directly related to severe clinical conditions of chronic gastritis, peptic ulcer, and gastric cancer. The virulence factors and the ability of these bacteria to form biofilms increase the resistance to conventional antimicrobials. In this sense, there is a growing interest in the search for new substances, among them of natural origin, as we…
Climate change, ineffective diagnoses, and uncontrolled use of antibiotics are factors that justify the emergence of new species of microorganisms with a high capacity for dissemination and mortality. This is the example of Candida auris, a yeast that appeared in Japan in 2009 and which today is a matter of worldwide concern due to its high resistance to therapy and mortality worldwide. A…
(Only some records are available in English at this moment)
Glioblastoma multiforme (GBM) is the most common primary malignant central nervous system cancer, responsible for about 4% of deaths associated with neoplasia, characterized as one of the most fatal human cancers. Chemotherapy is widely present in the treatment of glioblastoma and, among the commercial available drugs, docetaxel (DTX), Taxotere®, is a chemotherapy that has demonstrated ef…
Breast cancer can be defined as a malignant tumor of epithelial cells that develops in the breast, being considered the second most common type of cancer in the world, with estimated worldwide incidence of approximately 1.6 million of new cases per year. Among the drugs used in therapy, rapamycin stands out, traditionally used as an immunosuppressant and has demonstrated a potent activity…
Metal-organic frameworks (MOFs) are a class of highly porous materials that offer many opportunities for applications, including biology and medicine, highlighting as promising drug delivery systems (DDS) due to their great variability of compositions (metals, organic linkers), structural diversity (pore size, topologies) and high encapsulation capabilities of different active ingredients…
(Only some records are available in English at this moment)
| 3 / 3 | Ongoing research grants |
| 8 / 6 | Completed research grants |
| 7 / 7 | Ongoing scholarships in Brazil |
| 40 / 40 | Completed scholarships in Brazil |
| 6 / 6 | Ongoing scholarships abroad |
| 16 / 16 | Completed scholarships abroad |
| 80 / 78 | All research grants and scholarships |
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