CV Lattes
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ORCID
Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
master's at Immunology from Universidade de São Paulo (1998), ph.d. at Immunology from Universidade de São Paulo (2002) and ph.d. at Doutorado-Sanduích from Universidade de Paris VII Denis Diderot (2002). Has experience in Immunology, acting on the following subjects: melanoma b16f10, melanoma, carcinogenese, resposta inflamatória aguda and jararagina. (Source: Lattes Curriculum)
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The Butantan Institute is strongly committed to public health and, therefore, to actions related to combating COVID-19. The sectors or centers of the Butantan Institute, namely the Development and Innovation Center, the Scientific Development Center, the Bioindustrial Development Center and the Cultural Development Center, came together to develop projects to fight the pandemic. Consideri…
Malignant melanoma is a highly aggressive form of skin cancer with a high mortality rate if not discovered in early stages. Although a limited number of treatment options for melanoma currently exist, patients with a more aggressive form of this cancer frequently decline treatment. DM-1 is a sodium phenolate and curcumin analog with proven anticancer, anti-proliferative and anti-metastati…
In a recent report, we showed that synthetic phosphoethanolamine (Pho-s) has a broad antitumor activity on a variety of tumor cells and showed potent inhibitor effects on tumor progress in vivo. We show that murine renal carcinoma (Renca) is more sensitive to Pho-s when compared to normal immortalized rat proximal tubule cells (IRPTC) and human umbilical vein endothelial cells (HUVEC). In…
Boron neutron capture therapy (BNCT) is a binary treatment involving selective accumulation of boron carriers in a tumor followed by irradiation with a thermal or epithermal neutron beam. The neutron capture reaction with a boron-10 nucleus yields high linear energy transfer (LET) parlicles, alpha and 7U, with a range of 5 to 9 um. These parlicles can only travel very short distances and …
(Only some records are available in English at this moment)
Elucidate mechanisms of action and cellular signaling involved in the production of neutralizing antibodies and cellular immunity, mediated by T lymphocytes and the profile of pro- and anti-inflammatory cytokines. Development of a research platform for pre-clinical trials on GLP, in rodents and non-rodents. Study of the physiopathogenesis of SARS-Cov-2 in animal models.Training in the gui…
The Man's ability to replicate molecules of living beings, and to create other similar molecules, is a remarkable development in human history. Its birth dates back to 1828, when the German chemist Friedrich Wöhler synthesized urea molecule. Such molecules are usually known as natural products, a term which generally refers to secondary metabolites. Originally In the cancer treatment, ana…
Breast cancer is the second most deadly cancer for women worldwide, despite the various conventional approaches to radiotherapy, chemotherapy and hormone therapy. The resistance of tumor cells to chemotherapy is a major obstacle to the clinical success of cancer therapy. Triple-negative breast tumor is more aggressive than other subtypes of human breast cancer. The tumors that have higher…
In vitro study performed by our group demonstrated the efficacy of DODAC/PHO-S (dioctadecyldimethylammonium chloride/synthetic phosphoethanolamine) liposomal formulation on inhibition of cell proliferation and induced toxicity on B16F10 murine melanoma cells and Hepa1c1c7 murine hepatocellular carcinoma. Preliminary results obtained by our group (paper submitted for publication), demonstr…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 8 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 13 / 7 | Completed scholarships in Brazil |
| 23 / 13 | All research grants and scholarships |
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