Abstract
The cutaneous T-cell lymphoma (LCCT), non-Hodgkin lymphoma, has a more aggressive form: the Sézary Syndrome (SS). The malignant cells are the lymphocyte TCD4+, present in the peripheral circulation, skin, lymph nodes, and in some cases, viscera. An important immunological dysfunction occurs in SS patients, which contributes to the morbidity and mortality of the disease. The skin of SS pat…