Orlando Garcia Ribeiro Filho

• Abstract

  Ulcerative colitis (UC) is an inflammatory disease characterized by a chronic process of colonic mucosa damage. It is associated with an increased risk of carcinogenesis. The pathogenesis of the disease involves environmental and genetic factors with the active participation of phagocytic inflammatory cells, mainly activated macrophages. The most appropriate experimental study model for u…

  Study of the modulatory action of crotoxin on the evolution of experimental ulcerative Colitis, BP.IC

• Abstract

  Polycyclic aromatic hydrocarbons (PAHs) are aggressive factors found in the environment with potential carcinogenic and immunotoxic effects for humans and other species. Among the damages caused by PAHs we stand out those that directly affect the proliferative dynamics of hematopoietic cells. A prototype of PAH largely used in experimental research is 7.12 - dimethylbenzanthracene (DMBA),…

  Suppression of humoral and cellular immune response by 7,12-dimethylbenz (a) anthracene (DMBA) in AIRmax and AIRmin mice: correlation with AhR gene polymorphism, BP.IC

• Abstract

  Ulcerative Colitis (UC) is an inflammatory bowel disease characterized by a chronic process causing lesions of the colon mucosa and is correlated with an increased risk of carcinogenesis. Ulcerative Colitis development involves environmental and genetic factors being known as a multifactorial disease. Genetic studies have indicated an association between the Ahr gene variants (Aryl Hydroc…

  Influence of AhR gene on the development of ulcerative colitis by sodium sulfate of dextran in animal model of acute inflammation, BP.IC

(Only some records are available in English at this moment)