CV Lattes
ResearcherID
ORCID
Google Scholar Citations
Universidade Estadual de Campinas (UNICAMP). Centro de Hematologia e Hemoterapia (HEMOCENTRO) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Associate Professor of Hematology of the Department of Clinical Medicine, School of Medical Sciences, UNICAMP. Graduated in Medicine from the University of Campinas (1998), with specialization in hematology and hemotherapy (2001); PhD in Medical Physiopathology from the University of Campinas (2006). Areas of interest as a researcher are are the interactions between hemostasis and inflammation, and the diagnosis and management of disorders of hemostasis and thrombosis, and medical education. Member of the Technical Committee on Hemostasis of the Brazilian Association of Hematology and Hemotherapy, CNPa researcher and currently, Vice-Dean of the School of Medical Sciences of University of Campinas. (Source: Lattes Curriculum)
| News published in Agência FAPESP Newsletter about the researcher |
| TITULO |
| Articles published in other media outlets (0 total): |
| More itemsLess items |
| VEICULO: TITULO (DATA) |
| VEICULO: TITULO (DATA) |
Severe forms of COVID-19 are characterized by intense inflammation associated with significant increase in biomarkers of hemostasis activation. According to the concept of immunothrombosis, hemostasis and inflammation are intimately connected elements of the host response to pathogens. Based on this model, when regulated, local activation of hemostasis contributes to pathogen eradication,…
Thromboembolic disorders represent a major culprit for morbidity-mortality in Brazil and the World. The Hemocentro at Unicamp has a scientifically recognized research group, with over 100 highly cited publications in this field. We have revealed the roles of FVIII, VWF and of ADAMTS13 in Deep Venous Thrombosis (DVT) and severe Post-Thrombotic Syndrome (PTS); the association between hyperc…
Acute graft-versus-host disease (aGVHD) is a major cause of premature death in hematopoietic stem cell transplantation (HSCT). From classic studies conducted in the 1980s, the breakdown of intestinal epithelial barrier in the initial phase of HSCT has been recognized as a critical pathophysiological event for aGVHD. This breakdown allows the translocation of antigens from the intestinal l…
Febrile neutropenia in patients with hematological malignancies is a condition characterized by a high risk of sepsis and septic shock, resulting in the need for aggressive treatment for all patients. However, most patients with febrile neutropenia evolve without complications. Several inflammatory markers and clinical variables have been evaluated as biomarkers for risk stratification o…
Background: Febrile neutropenia carries a high risk of sepsis complications, and the identification of biomarkers capable to identify high risk patients is a great challenge. The VEGF/sFlt-1 axis is associated with the control of the integrity of the endothelial barrier function during embryonic angiogenesis. REcently, VEGF levels have been associated with mortality in intensive care unit…
(Only some records are available in English at this moment)
Febrile Neutropenia (NF) is a serious complication of antineoplastic chemotherapy, particularly in hematologic patients. Among the most feared complications of NF are Sepsis and septic shock. Despite advances in supportive therapy, the understanding of Sepsis pathophysiology remains incomplete, limiting the development of target-specific therapies. Studies in animal models and biomarkers …
Sickle Cell Disease (SCD) is the most frequent hereditary hemoglobinopathy in the world, which despite the advances in pathophysiological knowledge and in the treatment of support, continues to have a great negative impact on the quality of life and survival of patients. It has been known for at least 50 years that patients with SCD have elevated levels of free heme in circulation, associ…
Sickle cell disease (SCD) is a condition characterized by chronic inflammation and increased thrombotic risk in both arterial and venous beds. In the last decades, important advances were achieved in understanding the pathophysiology of hypercoagulability in these patients. However, several new mediators of coagulation activation have been recently described in other pathological contexts…
Thrombosis is the second leading cause of death in cancer patients. Thrombophilic state in cancer patients is multifactorial and involves factors of cancer itself, the interaction between cancer cells and normal cells, and treatments performed. Recently, the formation of NETs, neutrophils extracellular traps, was identified as a new factor related to higher risk of thrombosis in cancer pa…
Sepsis is one of the greatest challenges in medical practice, with mortality rates as high as 70% in most serious cases. However, its treatment is based mainly on the use of antibiotics and supportive therapy. Unlike areas such as oncology and rheumatology, in which targeted-specific therapies are being increasingly utilized, in the sepsis context this type of strategy has not been incorp…
(Only some records are available in English at this moment)
| 2 / 2 | Ongoing research grants |
| 6 / 4 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 7 / 6 | Completed scholarships in Brazil |
| 17 / 14 | All research grants and scholarships |
| Associated processes | |