CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de São José dos Campos. Instituto de Ciência e Tecnologia (ICT) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Associate Professor of Microbiology and Immunology in the Dentistry course at the Institute of Science and Technology ICT/UNESP-São José dos Campos and Researcher on Productivity at the National Counsel of Technological and Scientific Development/CNPq (PQ-1). Graduated in Dentistry (1998), Master in Oral Biopathology (2001) and PhD in Oral Biopathology (2003) at São Paulo State University/UNESP. Conducted a research internship at the Department of Infectious Diseases at Massachusetts General Hospital at Harvard Medical School in the United States (2010) and at the Department of Infectious Diseases at Rhode Island Hospital at Brown University in the United States (2014). Dr. Junqueira worked as Visiting Senior Professor at Brown University (USA) under the CAPES Chair Program (2016) and in the Microbiology and Infection Institute at the University of Birmingham (UK) under the CAPES-PRINT Program (2020). She was Coordinator of the Postgraduate Program in Oral Biopathology (2013-2016) and Coordinator of the Biohazard Committee (2007-2012) at ICT/UNESP. Currently, she is coordinator of the International Research Network ?Therapeutic, regenerative and restorative strategies for maintaining oral health? (CAPES/PRINT/UNESP), member of the Research Committee of ICT/UNESP and leader of the CNPq research group ?Models of experimental infection in invertebrates?. Coordinated 8 research projects funded by FAPESP (Regular Research Grants), coordinates an international research project funded by the Office of Naval Research Global (ONR/USA) and a Universal CNPq project. Participates grant reviewer to national and international research funding agencies, including FAPESP (Brazil), CNPq (Brazil), Narodowe Centrum Nauki (Poland), National Center for the Replacement, Refinement & Reduction of Animals in Research (United Kingdom) and Dutch Research Council (Netherlands). Dr. Junqueira published 18 book chapters and more than 130 articles in scientific journals, with approximately 1,500 citations and an H index equal to 25 in the Web of Science (Publons). Received more than 50 awards or honor in the scientific conferences. Participates as a member of the editorial board of Virulence (IF 4.77) and Journal of Fungi (IF 4.61) and as an ad hoc reviewer for Archives of Oral Biology, Brazilian Oral Research, Clinical Microbiology and Infection, Expert Review of Anti-Infective Therapy, Frontiers in Cellular and Infection Microbiology, Frontiers in Microbiology, Journal of Antimicrobial Chemotherapy, Journal of Photochemistry and Photobiology, Mycoses, Mycoscience, Photodiagnosis and Photodynamic Therapy, Pathogens & Diseases, Plos One, SpringerPlus and Yeast. Dr. Junqueira supervised several graduate students and scientific initiation. Currently, she supervises 3 post-doctoral students, 5 doctoral students, 1 master's and 4 undergraduate students. Develops projects in partnership with several national and international institutions. Has experience in Dentistry, with emphasis on Microbiology and Immunology, acting on the following subjects: oral microbiology, probiotics, photodynamic therapy, pathogen-host interaction and experimental infection models. (Source: Lattes Curriculum)
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The objective of this study will be isolate and identify strains of Lactobacillus spp. from the oral cavity of individuals caries free and to evaluate their probiotic action in Candida albicans and Streptococcus mutans by in vitro and in vivo studies. Saliva samples will be collected and identified by the API50CHL system and confirmed by Polymerase Chain Reaction (PCR). Thirty strains ide…
The interactions between fungi and bacteria are present in the nature and has great environmental and medical importance. The development of in vitro and in vivo models to characterize these interactions is essential for the understanding of the pathogenesis of the disease and the discovery of new therapeutic strategies. The aim of this study is to assess the microbial interactions betwee…
Whereas the high incidence of lesions of candidosis in immunocompromised patients and the emergence of non-albicans Candida species, which are often isolated in association with C. albicans in mixed infections, it becomes necessary to develop in vivo models in order to characterize the interactions among Candida species. This study will evaluate in vivo interactions between different Cand…
(Only some records are available in English at this moment)
Microcosm biofilms can mimic the biofilms of the oral cavity, being an important study tool in the investigation of therapeutic strategies for dental caries. Photodynamic Therapy (PDT) is considered a promising alternative for the treatment of this disease, however there is a need for more effective photosensitizers against dental biofilm. Therefore, the objective of this study will be to…
Photodynamic therapy (PDT) is a promising technique that can be used to control Streptococcus mutans. However, it has been necessary to identify photosensitizers with greater effectiveness against S. mutans and to understand how PDT acts on biofilms formed by these microorganisms. In this context, the objective will be to study the Fotoenticine® (FTC) activity in photodynamic therapy agai…
Photodynamic therapy (PDT) has been studied as a possible adjunct to treat dental caries. However, most of these studies were carried out with phenothiazine photosensitizers applied to monospecies biofilms. Then, the objective of this study will be to evaluate the effectiveness of photodynamic therapy mediated by a new photosensitizer, Fotoenticine® (FTC), in the treatment of oral micr…
E. Faecalis has great importance in persistent endodontic infections. Photodynamic therapy (PDT) has demonstrated the ability to reduce the growth of E. faecalis within the root canals, presenting potential to be used as a supporting endodontic conventional treatment. Aiming to increase the effectiveness of photodynamic therapy for the complete elimination of E. Faecalis, this work aims t…
(Only some records are available in English at this moment)
Currently, treatment options for fungal infections are limited due to the low availability of antifungal drugs and the rising of drug resistant strains. Thus, the development of new antifungal compounds and new therapeutic approaches are in great need for the control of these infections. The caffeic acid phenethyl ester (CAPE), caffeic acid (CA) and artepillin C (ARTC), compounds of propo…
In the last years, conventional antifungal screening strategies have failed to yield new classes of effective antimicrobials. New paradigms for discovering novel antimicrobial agents are needed. Ideally, new agents should be effective against persisters cells, the subpopulation of fungal cells that show tolerance to conventional drugs. This is clinically important because persister cells …
In vivo studies are fundamental to the study of microbial interactions of pathogenic microorganisms, and discovery of new antimicrobial agents. An animal model should reproduce the corresponding pathogenesis of infection in humans, including colonization and invasion from a specific route of entry and interaction with the host immune system. The aim of this study is to evaluate in vivo pr…
(Only some records are available in English at this moment)
| 9 / 5 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 27 / 19 | Completed scholarships in Brazil |
| 4 / 4 | Completed scholarships abroad |
| 41 / 29 | All research grants and scholarships |
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