CV Lattes
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Universidade de São Paulo (USP). Escola de Artes, Ciências e Humanidades (EACH) (Institutional affiliation for the last research proposal) Birthplace: Peru
bachelor's at Ciencias Biologicas from Universidade Ricardo Palma (1996) and doctorate at Pharmacology from Universidade de São Paulo (2004). Has experience in Biochemistry, acting on the following subjects: cancer, biologia molecular, bioinformatica, caquexia and envelhecimento. (Source: Lattes Curriculum)
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Background: FAM3B/PANDER is a novel cytokine-like protein that induces apoptosis in insulin-secreting b-cells. Since in silico data revealed that FAM3B can be expressed in prostate tumors, we evaluated the putative role of this cytokine in prostate tumor progression.Methods: FAM3B expression was analyzed by quantitative PCR in tumor tissue clinical samples and LnCAP, PC-3, and DU145 prost…
The PANDER/FAM3B (pancreatic-derived factor) was recently identified as a novel cytokine expressed almost exclusively by the pancreatic islets. It was demonstrated that PANDER induces apoptosis in insulin secreting beta-cells. However, our in silico data revealed that the PANDER gene is also expressed in prostate and breast tumors. Our goal is to evaluate the functional role of PANDER in …
The PANDER/FAM3B (pancreatic-derived factor) was recently identified as a novel cytokine expressed capable to induce apoptosis in insulin secreting beta-cells. However, PANDER gene is also expressed in prostate and breast tumors. Our goal is to evaluate the pro-apoptotic properties of PANDER in prostate carcinoma (DU145) and breast adenocarcinoma (MDA-MB-231) stably over-expressing PANDER…
| 3 / 2 | Completed research grants |
| 2 / 1 | Completed scholarships in Brazil |
| 5 / 3 | All research grants and scholarships |
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