Degree in Medicine from the School of Medicine of Ribeirão Preto / USP (1991). Masters (1994) and Ph.D. (1999) in Physiology also from the School of Medicine of Ribeirão Preto / USP. Sandwich PhD (1998) and Postdoctoral (2007-2009) in the Cardiovascular Center, University of Iowa, USA. Associate Professor in the Department of Physiology, School of Medicine of Ribeirão Preto / USP, with experience in Physiology of the Cardiovascular System, acting on the following subjects: neural control of circulation and experimental models of cardiovascular diseases, heart rate variability. (Source: Lattes Curriculum)
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The Autonomic Nervous System (ANS) - Sympathetic and Parasympathetic - plays a role in the physiopathogenesis of cardiovascular diseases. Overall, there is a Sympathetic Overactivity contrasting with the Attenuation of Parasympathetic Function. It has also been demonstrated an interaction between the ANS and the Immune Systems (Innate and Adaptive), despite the mechanisms involved require…
The present study was grouped into five Projects investigating the cardiovascular regulation under physiological - Project 1 - and physiopathological - heart failure (HF) - condition, i.e. Project 2, 3, 4A e 4B.Project 1 aims to characterize the presence of substance P in the axons of the aortic depressor nerve (ADN) and nodose ganglion. To accomplish this, it will be used immunohistochem…
Heart failure (HF) is characteristically accompanied by a remarkable increase in the sympathetic activity. Several studies have shown that peripheral chemoreceptors (powerful sympathetic stimulators) have augmented sensitivity in both patients and experimental models of HF. The present study aims to evaluate the chemoreceptors influence on autonomic cardiovascular modulation and cardiac f…
(Only some records are available in English at this moment)
Doxycycline (DOXI), a large spectrum antibiotic, when administered in low doses (non-antimicrobial) has an inhibitory effect on extracellular matrix metalloproteinases (MMP), inflammatory mediators and effector molecules associated with myocardial infarction (MI). Studies have shown that DOXI reduces ventricular remodeling and decreases the susceptibility to cardiac arrhythmias after MI. …
Restoration of coronary flow is one of the main therapeutic tool to minimize the damage caused by acute myocardial infarction, however, it may have deleterious effects on the heart, a phenomenon known as myocardial ischemia/reperfusion injury (RI). The study of the mechanisms involved in IR injury and the knowledge of therapeutic strategies to protect the heart from IR damage are an impor…
Acute myocardial infarction (MI) is a major health problem due to its high incidence and mortality. The MI is always accompanied by a dysautonomia characterized by sympathetic overactivity and decreased cardiac vagal tone. Life threatening cardiac arrhythmias are commonly seen in patients with MI. It is consensual, and the issue of intense research, that sympathetic hyperactivity is delet…
Essential hypertension affects about 35% of the population above 40 years of age and is strongly associated with increased risk of serious cardiovascular events. Hypertension affects various organs such as the heart, blood vessels, and kidneys, as well as affects cardiovascular autonomic modulation leading to sympathetic hyperactivity and reduced vagal parasympathetic drive to the heart. …
The main cause of cardiac arrhythmias after acute myocardial infarction (AMI) is the electrical instability of cardiomyocyte membrane caused, among other causes, the deterioration of the protein responsible for maintaining the integrity of gap junctions present in the heart. The most important and abundant of these is the connexin 43 (Cx43). Evidences point out for an anti-arrhythmogenic …
| 1 / 1 | Ongoing research grants |
| 6 / 4 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 3 / 3 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 12 / 10 | All research grants and scholarships |
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CV Lattes
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