Abstract
Approximately 5-10% of all cancers are inherited. Some tumors and inherited syndroms are related to germline mutations in specific genes. Hereditary breast cancer results from mutation in BRCA1 and BRCA2, and a deletion in CHEK2 is associated with a two fold increased risk to develop this desease. The Lynch Syndrom is associated with mutation in the repare genes and constitutes a risk fac…