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Marciane Milanski Ferreira

CV Lattes ResearcherID ORCID Google Scholar Citations


Universidade Estadual de Campinas (UNICAMP). Faculdade de Ciências Aplicadas (FCA)  (Institutional affiliation for the last research proposal)
Birthplace: Brazil

1993 1997 B.S. in Nutrition, Federal University of Mato Grosso, UFMT, Brazil; 1997 1998 Specialization in Public Health, University of Ribeirão Preto, UNAERP, Brazil; 2003 2005 M.S. in Health Sciences, Federal University of Mato Grosso, UFMT, Brazil; 2007 2008 Ph.D. in Biochemistry, University of Barcelona, Spain; 2005 2009 Ph.D. in Medical Clinic University of Campinas, UNICAMP, Brazil; 2009 2011 Postdoctoral Training in Medical Clinic University of Campinas, UNICAMP, Brazil; 2016 - 2017 Visiting Professor Cell Biology Program SickKids Research Institute/Toronto-CA; 2017 2017 Visiting Professor - Université PARIS- DIDEROT 7/França MAIN INTEREST IN RESEARCH - Role of lipid excess (saturated fat acids and interesterified lipids) in the development of obesity and type 2 diabetes. Metabolic and molecular aspects. Significant scientific contributions: - Characterization of the role of high-fat diets in body energy homeostasis and the mechanisms involved in hypothalamic resistance to leptin and insulin. - Identification of TLR4 activation and subsequent induction of endoplasmic reticulum stress as mechanisms involved in hypothalamic resistance to leptin and insulin. Central inhibition of inflammation in DIO animals, by blocking the activation of TLR4 or ER stress was able to reverse the glucose homeostasis in part by inhibition of hepatic glucose production. - Role of hypothalamic autophagy in the regulation of glucose homeostasis induced by obesity - Characterization of the role of interesterified fat in metabolism. Interesterified soybean oil promotes weight, impaired glucose tolerance and increase liver cellular stress markers in Swiss mice. (Source: Lattes Curriculum)

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