Abstract
The aim of this study is to evaluate the proteolysis of histatins 1 and 5 in whole saliva of subjects with Down syndrome (DS) and periodontal disease (PD), as well the antibacterial function of the degradation products. Twenty four subjects will be selected and equally divided in the following groups (n=6): DS with PD (Group DS/+PD), DS without PD (Group DS/-PD), non-syndromic with PD (Gr…