Abstract
Our ability to sense heat, cold, touch or pain is essential for survival and underpins our interaction with the world around us. TRPV1 is the sensor that responds to heat and activates nerve cells causing pain sensations. How TRPV1 exerts this function is still an unsolved riddle. The processes of phosphorylation and dephosphorylation by kinases are crucial for TRPV1 function. Recent data…