Abstract
It is known that the binding affinity between the Spike (S) protein and the angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease II (TMPRSS2) receptors is one of the main determining factors in the replication rate of SARS-CoV -2 (Severe Acute Respiratory Syndrome coronavirus-2) and that such interactions directly affect the clinical condition of the patient. SARS-CoV-…