Abstract
Bisphosphonates (BFS) have been extensively used to treat diseases of bone metabolism, especially in the prevention of bone metastases, Paget's disease and the prevention and treatment of osteoporosis and osteopenia. However, there are undesirable side effects as the induction of Osteonecrosis of the Jaws (bisphosphonate-related osteonecrosis of the jaws - BRONJ), a complication of diffic…