CV Lattes
Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) (Institutional affiliation from the last research proposal) Birthplace: Brazil
bachelor's at Farmacia from Universidade Federal do Rio de Janeiro (2006), master's at Chemistry from Universidade Federal do Rio de Janeiro (2008) and doctorate at Chemistry from Universidade Estadual de Campinas (2014). Has experience in Chemistry, acting on the following subjects: coumestan, pterocarpene and intramolecular heck reaction. (Source: Lattes Curriculum)
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Tautomycetin (TTN) is natural polyketide isolated in 1989 from Streptomyces griseochromogenes. TTN is more seletive inhibitor of PP1 (serine/threonine phosphatase) known until now and it is a potent protein tyrosine phosphatase-2 (SHP2) inhibitor. The phosphatases protein have been investigated as a new strategy for cancer therapy. This project aim to develop a convergent synthetic route …
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