Abstract
The malfunction of cortico-striatum-thalamic-cortical (CSTC) circuitry is involved in several neuropsychiatric disorders, specially obsessive-compulsive disorder (OCD). The observation that OCD patients improve following treatment with selective serotonin re-uptake inhibitors (SSRI) leaded to implicate this system in this pathology. However OCD pharmacotherapy is effective in less than ha…