Abstract
The in-stent reestenosis is observed in 20-25% of percutaneous transmural coronary angioplasty (PTCA) following bare metal stent implantation. Smooth muscle cells (SMC) differentiation and proliferation, deposition of extra - cellular matrix and adjacent endothelial prejudice are the triggers for its formation. Neointima can be prevented by drug-elution stents, such as nitric oxide (NO) d…