Abstract
In Duchene Muscular Dystrophy (DMD) and in mdx mice, an experimental model of DMD, the absence of the protein dystrophin leads to muscle degeneration. It is believed that the pathogenesis of DMD is related to sarcolemma fragility, mechanical stress, and malfunction of calcium channels in the muscle fiber. The pathways knowledge involved in muscle degeneration/regeneration and in the prote…