Bachelor's at Biological Sciences by the Universidade Estadual Paulista Júlio de Mesquita Filho (1994), master's and Doctorate's at Cell Biology by the Universidade Estadual de Campinas (1997) (2001). Has experience in Morphology, acting on the following subjects: extracellular matrix, prostate, matrix metalloproteinases, bone, cartilage and tendon. (Source: Lattes Curriculum)
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Prostate Cancer (PCa) is the second most frequent and the second highest rate of morbidity and mortality among men. Studies highlight the role of obesity and the extracellular matrix in the progression of PCa to the more aggressive, metastatic and resistant state to antiandrogenic, chemotherapeutic and radiotherapeutic therapies. Transcriptome analyzes of transgenic mouse models for prost…
Prostate cancer (PCa) is the second most frequent and the second highest rate of morbidity and mortality among men. Studies highlight the role of stroma in the initiation and progression of CaP, as well as oxidative stress and kinase enzymes. In a previous project with the collaboration of the University of Cambridge-UK, two strains of knockout mice, one deficient in Pten and other defici…
Prostate cancer (PCa) is the most common malignancy in men and the second leading cause of male cancer-related deaths in the Western world. The Pten, p53 and pRb tumor suppressor genes are the most frequently mutated/deleted in various human cancers, including PCa. Recent studies emphasize the role of oxidative stress in the initiation and progression of PCa. This project aims to evaluate…
(Only some records are available in English at this moment)
Obesity increases the propensity to develop other diseases, such as hypertension and dyslipidemia, in addition to several types of cancer, including prostate cancer (CaP). Excess of adipose tissue is responsible for altering the production and secretion of various adipokines, such as adiponectin. This adipokine has anti-diabetic, anti-inflammatory, and cardioprotective effects, however, c…
Prostate cancer (CaP) is the second most prevalent cancer in men in Brazil and worldwide. For localized tumors, available treatments have allowed a high rate of cure and survival with the disease. For metastatic tumors, cure rates decrease considerably but can be controlled initially with anti-androgenic therapies. However, most metastatic tumors evolve to their lethal form that is resist…
Perinatal protein restriction (RPP) has been associated with an increase in the incidence of cardiovascular and renal diseases, besides affecting reproductive parameters and the development of some types of cancer. In addition, exposure of these individuals to a second insult in postnatal life may amplify the damage caused by RPP by increasing the incidence of these diseases with aging. O…
Prostate cancer (PCa) is the second most frequent and with a higher rate of morbidity and mortality among men. Studies highlight the role of intestinal metaplasia in the process of tumor progression and invasion. However, more studies are needed to understand how this metaplasia is related to the development of castration-resistant PCa. Thus, this project aims to describe the incidence, m…
(Only some records are available in English at this moment)
Prostate cancer (PCa) is the most common malignancy in men and the second leading cause of male cancer-related deaths in the Western world. The Pten, p53 and pRb tumor suppressor genes are the most frequently mutated/deleted in various human cancers, including PCa. Recent studies emphasize the role of oxidative stress in the initiation and progression of PCa. This project aims to evaluate…
| 11 / 6 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 30 / 16 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 43 / 24 | All research grants and scholarships |
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CV Lattes
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