CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Biologia from Universidade de Passo Fundo (1985), master's at Fisiologia e Biofísica from Universidade Estadual de Campinas (1991) and doctorate at Fisiologia e Biofísica from Universidade Estadual de Campinas (1997). Has experience in Physiology, acting on the following subjects: aprendizagem, ginkgo biloba, labirinto em cruz elevado, aprendizagem e memória and plasticidade neural. (Source: Lattes Curriculum)
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Alzheimer's disease (AD) is the most frequent cause of dementia associated with aging, occurring with higher prevalence in women. Among the factors associated with the disease are the alteration in the function of acetylcholine vesicular transporter (VAChT) in the prefrontal cortex (CPF) and in the hippocampal formation (FH) of patients with AD. Another risk factor associated with AD is i…
Previous studies from our group have demonstrated that the dorsal hippocampal formation (DHF) has been one of the main targets for modulation of drugs during acquisition and extinction of conditioned suppression, a suitable animal model for investigating the behavioral changes and pharmacological mechanisms that underlie fear memory and anxiety. The participation of DHF in these process, …
The major research interest of our laboratory is to gain substantial knowledge on the molecular and cellular basis underlying the acquisition and extinction of conditioned fear, which will enable the understanding of changes previously described by our group after treatment with the standardized extract of Ginkgo biloba L. (EGb). Additionally, this study may provide new pharmacological ap…
(Only some records are available in English at this moment)
Alzheimer's disease (AD) is considered the main cause of dementia among the elderly, being characterized by progressive loss of cognitive function, and is directly correlated with the cognitive decline observed in patients with type 2 Diabetes mellitus (DM2), elucidating the term type 3 Diabetes to represent AD. In this context, of an extremely important need for new therapies to be disco…
The actions of standardized extract of Ginkgo biloba (EGb) the improvement of memory has been demonstrated by our group from data which showed that conditioned suppression resulted in increased expression of CREB-1 (mRNA and protein) in the dorsal hippocampus of rats. Understanding these effects is needed for studies on the molecular mechanisms associated with this modification. Several s…
(Only some records are available in English at this moment)
| 7 / 6 | Completed research grants |
| 6 / 4 | Completed scholarships in Brazil |
| 13 / 10 | All research grants and scholarships |
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