Abstract
Multiple Endocrine Neoplasia Type 2 (MEN2) is an autosomal dominant genetic disorder characterized by the association of endocrine tumors. MEN2 is classified into two subtypes, MEN2A and MEN2B, according to the affected organs. The most important clinical manifestation of MEN2 is the medullary thyroid carcinoma (MTC), occurring in more than 95% of patients. Mutations in the RET (REarrange…