CV Lattes
ORCID
Abstract
The primary pathophysiological mechanism involved in Alzheimer's disease (AD) is related to the extracellular formation of amyloid ² (A²) plaques. This change is highly neurotoxic, resulting in synaptic damage and increased oxidative stress, with a local inflammatory response followed by neuronal death. Neuroinflammation also inhibits neurogenesis, contributing to neural stem cell (NSCs) …