Abstract
The Oral Squamous Cell Carcinoma (OSCC), the main subtype of cancer in the oral cavity, is characterized by a poor prognosis, resulting from a very aggressive local growth and high rates of locoregional recurrence. The treatment of choice for OCCs is surgery, with radiotherapy and/or chemotherapy being applied as adjuvants. Cisplatin is the most used chemotherapeutic drug for the treatmen…