CV Lattes
ORCID
Abstract
Mitochondria is an organelle present in most eukaryotes that plays a key role in energy generation processes, being essential for cellular homeostasis. Mitochondrial DNA (mtDNA) encodes 37 genes, including 2 ribosomal RNAs, transport RNAs and 13 polypeptides, components of 4 of the five oxidative phosphorylation protein complexes. Somatic mutations in this genome accumulate in cancer and …