Abstract
Phospholipases A2 are a large family of enzymes that have the function of hydrolyzing the sn2 phosphodiester bond of phospholipids and releasing fatty acids, emphasizing unsaturated fatty acids of 18 to 20 carbons (PUFAs, w-3 and w-6) and acid arachidonic (C20: 4 w-6), whose subsequent metabolization by cyclooxygenase 2 (COX-2) generates bioactive pro-inflammatory and homeostatic lipids. …