Abstract
Panic Disorder (PD) is characterized by the presence of recurrent Panic Attacks (PA), with intense fear, sensation of suffocation, and cardiovascular perturbations posing as main symptoms of PD. Both clinical and pre-clinical data support the Dorsal Periaqueductal Gray (DPAG) as a key brain structure implicated in the pathophysiology of PD. Additional exper-iments in rodents also indicate…