Abstract
In model eukaryotes, inositol pyrophosphates (PP-IPs) - mainly PP-IP4, IP7 and IP8 - are involved in a wide range of processes, such as regulation of telomere length, and homologous recombination (HR). However, the PP-IPs target-proteins, as well as their action mechanisms remains unknown. PP-IP4, IP7 and IP8 are synthesized by pathways involving the participation of IP6K and PP-IP5K kina…