Has experience in Biochemistry, focusing on Biochemistry (Source: Lattes Curriculum)
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The response to genomic damage involves several effector proteins that act in many cellular processes promoting adaptations and changes in the organism and its genomes, such as re-establishment of nuclear function (through DNA lesions repair and nuclear proteins) and cellular metabolic reprogramming. Failures to trigger an appropriate cellular response during the genotoxic stress can lead…
The Dpb11 protein (ortholog of human TopBP1) is an essential protein acting in several aspects of the cellular program such as replication, DNA damage signaling/repair and recombination. As part of the DNA damage response, Dpb11 has a key regulatory role in DNA damage checkpoint through the interaction between its BRCT domains (BRCA1 C-terminal domain) and phosphorylated residues in prote…
| 2 / 2 | Completed scholarships in Brazil |
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CV Lattes
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