CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduation at Ciências Biológicas from Universidade Federal de São Paulo (2021). Has experience in Biochemistry (Source: Lattes Curriculum)
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The use of high-capacity adenovirus vectors in cancer therapy has been promising. These vectors are considered safer and with higher cloning capacity in comparison to first and second generations adenovirus vectors. Different approaches can be explored while using adenoviruses as gene carriers, such as inducing the expression of antitumor genes or deleting pro-tumor genes, both leading to…
Gene therapy using viral vectors has a great potential, which is already being used in human clinical protocols. Medullary thyroid carcinoma represents the thyroid malignancy with worst prognosis, featuring great clinical relevance and an ineffective treatment. The development of new therapies, including gene transfer, could be a good option. The Herpes simplex thymidine kinase (HSVtk) ge…
The development of head and neck cancers is usually associated with alcohol consumption and tobacco use, besides of HPV infection. The HPV, through its virals oncoproteins E6/E7 alters the proteins p53, pRb and others. The p53 protein is also frequently altered in HPV negative tumors given that its function is related to response of cellular stress, and could lead cell to apoptosis or sen…
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