CV Lattes
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Universidade Federal de São Carlos (UFSCAR). Centro de Ciências Biológicas e da Saúde (CCBS) (Institutional affiliation for the last research proposal) Birthplace: Brazil
Doctorate student at the Post-Graduate Program of Evolutionary Genetics and Molecular Biology (PPGGEv) of the Federal University of São Carlos. Bacharel of Science in Biology by the Federal University of São Carlos partially completed at the University of Sheffield (England). Experienced in Biochemistry and Molecular Biology, with previous works on adaptive biochemistry, recombinant protein expression and purification, cancer (particularly on tumour angiogenesis and extracellular vesicle studies). Student's representative at PPGGEv since June 2021. Participant of the Brazilian Reproducibility Initiative (LAB43). (Source: Lattes Curriculum)
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Extracellular Vesicles (EV) are structures able to carry biomolecules stably, whose function is mainly of cell-cell communication. During Cancer development, the establishment of hypoxia stimulates the secretion of tumour derived EVs, which will act in all the steps of the metastatic cascade, especially in the communication between cells of the Tumour Microenvironment (TME). Signalling fr…
Breast cancer is the main cause of mortality amongst Brazilian women, especially due to metastasis, in which tumour cells lose adhesion to the tissue, acquire a mesenchymal phenotype and invade adjacent and distant tissues. Cellular invasion is dependent on the interaction between adhesion receptors and extracellular matrix (ECM) components, which is constantly remodelled by tissue cells.…
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