Abstract
As demonstrated in the research plan, our omega-3 lipid metabolites are likely to modulate liver function by reducing hepatic lipogenesis and glucose production.Our data also suggest a role for Scd1 in mediating the lipids effects. Scd1 appears to be a major regulator of liver lipogenesis, and its increased activity leads to increased monounsaturated fatty-acids (MUFAs) levels and consequ…