Abstract
It is known that adipose tissue-secreted lipid metabolites, the so called lipokines, are able to induce beneficial effects on glucose and lipoproteins homeostasis. Invariably, these effects are mediated by the G-Protein Coupled Receptors (GPCR), thus activating signaling cascades in a manner similar to the classic hormones. GPCRs are a large family of receptors with seven transmembrane pr…