Abstract
6-nitrodopamine (6-ND), a product of the nitric oxide (NO) dependent nitration of dopamine (DA), produced endogenously. Increased evidence shows its role as the most potent mediator of in vivo and in vitro chronotropism in rats, and the spasmogenic activity of the vas deferens in rats and humans. In other tissues of the genitourinary tract, the production, release and function of 6-ND is …