Abstract
Hepatitis C is an infectious disease that affects the liver that can progress to cirrhosis, hepatocarcinoma and death. The causative agent is the Hepatitis C Virus (HCV), a positive single-stranded RNA virus that belongs to the Flaviviridae family. Due to its high mutation rate, associated with the large daily production of viruses and the lack of proofreading activityof the NS5B viral po…