graduation at Ciências Biolóicas from Universidade de São Paulo (2005), master's at Neurociências e Ciências do Comportamento from Universidade de São Paulo (2009) and doctorate at Neurociências e Ciências do Comportamento from Universidade de São Paulo (2013). Has experience in Physiology, acting on the following subjects: parkinson, eletrofisiologia, doença de parkinson, neurociências and discinesias induzidas pela l-dopa. (Source: Lattes Curriculum)
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Pharmacotherapy of Parkinson's disease (PD) is mainly based on the dopamine precursor L-DOPA. However, long-term treatment with L-DOPA has been associated with unwanted side effects called L-DOPA-induced dyskinesias (LID). Compounds that interfere with cyclic nucleotides (cAMP/cGMP) availability, such as phosphodiesterase (PDE) inhibitors, are emerging as a promising anti-dyskinetic co-th…
Parkinson's Disease (PD) is a progressive neurodegenerative disorder that affects 1% of people over the age of 60. The primary motor symptoms of PD include resting tremor, slowness of movements, rigidity and postural instability. These symptoms result from the degeneration of the dopaminergic cells in the Substantia Nigra pars compacta (SNc). L-DOPA remains the gold standard treatment for…
Alzheimer's disease (AD) is a major neurocognitive disorder that causes progressive deficits in cognition, learning and memory. AD etiology has been attributed to the accumulation of ²-amyloid protein that lead to the formation of amyloid plaques and neurofibrillary tangles (NFT). Brain areas such as the hippocampus and the amygdala are stricken by these pathological alterations, causing …
Among the main pathological evidence affecting Parkinson's disease (PD) patients is the death of dopaminergic neurons of the substantia nigra pars compacta. Dopamine replacement can be done with L-3,4-dihydroxyphenylalanine (L-DOPA) but chronic use of this drug is associated with the onset of motor complications known as L-DOPA-induced dyskinesias (LIDs). Inhibition of the phosphodiestera…
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Local field potentials (LFPs) are generated by large populations of neurons and resemble a sum of signals from neurons present in the vicinity of the recording electrode and represent a technique increasingly used to measure the transmission of neural networks. Our laboratory in Brazil uses animal models of Parkinson's disease to investigate the impact of chronic chronic administration of…
| 3 / 3 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 11 / 10 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 16 / 15 | All research grants and scholarships |
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CV Lattes
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