Leonardo Luís Artico in research grants and scholarships supported by FAPESP.
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Acute Lymphoblastic Leukemia (LLA) is the most common type of Cancer in childhood, accounting for about 30% of all Cancers and 80% of all leukemias occurring up to the age of 15 years. In the previous work, we verified that leukemic cells secrete several proteins, among them IGFBP7, which together with their ligands (insulin, IGF1 and IGF2) stimulate bone marrow stromal cells to produce a…
Acute Lymphoblastic Leukemia (ALL) is the leading cancer in children. Several studies show that the interactions between leukemic blasts and bone marrow stromal cells (OM) contribute to the resistance of ALL to chemo. In the previous work, we verified that leukemic cells secrete several proteins, among them IGFBP7, which together with their ligands (insulin, IGF-1 and IGF-2) stimulate MO …
Insulin and insulin-like growth factors (IGFs) are mitogenic and pro-survival factors to many different cell types. Circulating IGFs are bound by IGF binding proteins (IGFBPs) that regulate their action. IGFBP7 is a novel IGFBP-related protein (IGFBP-rP) that, in contrast to other IGFBPs/IGFBP-rPs, features higher affinity for insulin than for IGFs. We previously demonstrated that IGFBP7 …
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 3 / 3 | All Scholarships |
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