Abstract
Reactions of NO* with O2, or with O2.-, leads to the formation of reactive nitrogen species (RNS) whose activity may be responsible for the effects attributed to NO*. RNS promote oxidative modifications in amino acids, or react with the iron-heme group in proteins/enzymes modulating cell signaling processes (Pacher et al, 2007). Oxidative-based post-translational modifications can positiv…