graduate at Odontologia from Faculdade de Odontologia de Araraquara (2005). Has experience in Odontology, focusing on Periodontology, acting on the following subjects: odontologia. (Source: Lattes Curriculum)
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Periodontitis shares chronification and persistent low-grade inflammation with many chronic diseases, including rheumatoid arthritis, colitis, and Crohn's disease. In all these conditions, there is a gradual impairment of the immune response that can modify the susceptibility and severity of the disease. Furthermore, the concomitant development of other chronic diseases, e.g., arthritis a…
Chalcones are a group of plant-derived phenolic compounds with diverse biological properties such as anti-inflammatory, antioxidant, antimicrobial and anti-resorptive. Due to their pharmacological effects, different natural and synthetic chalcone derivatives have been investigated as therapeutic agents. Clinical and preclinical studies have demonstrated its effectiveness in the treatment …
Inflammation is proposed as the 7th hallmark of cancer as it is associated with virtually all solid tumors, including oral cancer. Paradoxically, the immune response, which is supposed to detect and clear defective / transformed cells may play roles in both tumor initiation and progression. This has led to the anthropomorphization of the immune response as 'good' or 'bad', depending on th…
The production of antioxidant enzymes, necessary to counteract the harmful effects of oxidative stress, is in part regulated by the Nrf2 signaling pathway (nuclear erythroid factor 2 related factor 2). In addition to acting on the activation of antioxidant factors, Nrf2 is able to inhibit the activation of inflammatory cytokines and chemokines and transcription factors involved in the mod…
Periodontitis shares chronification and persistent low-grade inflammation with many chronic diseases, including rheumatoid arthritis, colitis, and Crohn's disease. In all these conditions, there is a gradual impairment of the immune response, increasing susceptibility to infections. Cytokines relevant in inflammatory diseases such as rheumatoid arthritis and periodontitis act through the …
Oxidative stress, defined as the imbalance between the production of reactive oxygen species (ROS) and antioxidant mechanisms, has been correlated with the pathogenesis of a number of inflammatory diseases, including periodontal disease. The exaggerated production of ROS can increase the oxidative damage of proteins in the periodontium and contribute to tissue destruction. The production …
Many cytokines with biologically relevant functions in inflammatory diseases such as rheumatoid arthritis and periodontal disease exert their biological functions through the JAK-STAT signal transduction pathway. Activated JAKs phosphorylate the receptor's cytoplasmic domain, inducing the activation of its substrates, mainly proteins known as STATs, which in turn dimerize and translocate …
Chalcones are a group of phenolic compounds derived from plants, with diverse biological properties. Due to their pharmacological effects, different synthetic chalconic derivatives, based on their natural analogues, have been investigated as therapeutic agents. Clinical and preclinical studies have demonstrated its effectiveness in the treatment of inflammatory diseases such as cancer and…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 2 / 2 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 16 / 15 | Completed scholarships in Brazil |
| 21 / 20 | All research grants and scholarships |
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CV Lattes
ORCID