Maria Julia Bistaffa in research grants and scholarships supported by FAPESP.
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Lung cancer has the second highest incidence worldwide, with an estimated 2.2 million new cases and 1.8 million deaths during the year 2020. Platinum derivatives, such as cisplatin, are chemotherapeutic agents used for more than 40 years in the treatment of lung cancer, and its clinical application faces problems related to chronic dose-dependent adverse effects. The non-selective distrib…
The photodynamic therapy (PDT) has been outstanding as a promising alternative for treating several diseases. However, the lack of detailed knowledge on the mechanisms of action prevents exploitation of the therapy full potential. In this research project we shall investigate the cellular cytotoxicity derived from the action of erythrosin B photosensitizer, a compound derived from the fam…
Cancer is responsible for six million deaths annually. Despite the widespread use of chemotherapy to control neoplastic growth, numerous challenges such as lack of specificity, adverse effects, and resistance due to tumor heterogeneity are encountered. Doxorubicin (DOX) is a widely used anticancer drug to treat various cancer types. However, they are associated with limitations such as no…
Giant Unilamellar vesicles (GUVs) have been shown to be one of the best primary cell models in terms of size (10 - 50 ¼m), membrane composition and ability to encapsulate biologically relevant molecules. In this project, we shall evaluate the radiation-induced modifications on GUVs as outcome of the lipid oxidation induced by erythrosin B. In analogy to natural cells, composed of several …
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 1 / 1 | Completed scholarships abroad |
| 4 / 4 | All Scholarships |
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