Bachelor's Degree in Biological Sciences from the University of Mogi das Cruzes (2003), Master's and Ph.D. in Sciences from the Department of Nephrology, Hospital das Clínicas, Faculty of Medicine, University of São Paulo (2010, 2014). Since 2005, she has been a Biologist at the Medical Research Laboratory-12 (LIM12) at the Hospital das Clínicas of the University of São Paulo (HC-FMUSP). He has experience in Physiology and Pathophysiology, with an emphasis on Renal Pathophysiology, working mainly on the following topics: cell signaling pathways, cell proliferation and death and models of nephrotoxicity, acute and chronic kidney injuries. Currently, he participates intensively in the insertion of studies and discoveries on the influence of vitamin D in models of kidney disease. (Source: Lattes Curriculum)
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Acute kidney injury (AKI) associated with vitamin D deficiency (VDD) potentiates the injury and may accelerate the renal disease progression (RDP). On the other hand, we demonstrated that vitamin D replacement in ischemic-AKI associated with VDD mitigated the RDP. Cytosolic sulfotransferase enzymes (SULTs) regulate the synthesis and biological activity of various hormones, in addition to …
Acute kidney injury (AKI) alters renal hemodynamics, leads to tubular injury, activates inflammation pathways, proliferation, and cell death. The initial damage caused in renal tissue after an ischemia/reperfusion (I/R) event suggests an important role in the pathogenesis of AKI course. Likewise, the establishment of the disease may lead to predisposition to chronic kidney disease (CKD). …
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