Abstract
Lipid mediators such as prostaglandins (PGs), leukotrienes (LTs), lipoxins (LXs) and Platelet Activator Factor (PAF) are important in the development and/or resolution of the inflammatory response. The biosynthesis of eicosanoids (EIC) and PAF involves activation of the enzyme phospholipase A2 (PLA2) and subsequent release of arachidonic acid (AA) and lyso-PAF. Free AA is then oxygenated …