Abstract
Previous results have demonstrated that peptides derived from CDRs immunoglobulins exhibit activity in vitro and in vivo against human cancer cell lines and against murine melanoma B16F10-Nex2 in syngeneic model C57BI6 H-2b mice. (Arruda et al, 2012; Dobroff et al., 2010). Anti-tumor effects observed after intraperitoneal injection of peptides could be reproduced using syngeneic dendritic…