Bachelor of Biotechnology at the Federal University of Bahia, has always been involved in activities related to academic research, with the main interest the health research. (Source: Lattes Curriculum)
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Marfan Syndrome (MFS) is an autosomal dominant connective tissue disease that primarily affects skeletal, ocular and cardiovascular systems, been Aortic Aneurysm responsible for most morbidity and mortality. MFS is caused by mutations in the fibrillin-1 gene (FBN1), one of the main structural components of the extracellular matrix and responsible for regulating TGF-² activity. MFS has imp…
The Marfan syndrome (SMF), caused by mutations in the fibrillin-1 gene elastic matrix, whose main phenotype aortic aneurysms, valvular heart disease and cardiomyopathy. Several mechanisms are linked to the pathophysiology of SMF, especially signaling via angiotensin AT1 receptor, TGF-² and its non-canonical pathway involving the kinase ERK. Studies from our group indicate that redox pathw…
| 2 / 2 | Completed scholarships in Brazil |
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