Willian Robert Gomes in research grants and scholarships supported by FAPESP.
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Telomeres are complex structures made up of repetitive nucleotide sequences that associate with proteins to form the ends of linear chromosomes. Telomeric extension decreases with each mitotic cycle and once the telomere length becomes too short, it induces cells to enter senescence or apoptosis. Some cell types, such as embryonic or adult stem cells, must maintain their proliferative cap…
Previous data in the literature suggest that exposure to lead (Pb) results in disorders of cellular redox status leading to oxidative stress and consequently, may cause damage to macromolecules, such as lipids, proteins and DNA. However, most of the work was performed in vitro or in animals models and very little is known about the possible adverse effects related to disturbances of the r…
Telomeres are the repetitive nucleotide structures at the end of linear chromosomes that, when critically short, engage cell senescence, apoptosis, or chromosome instability. In cells with high proliferative demand, telomeres are repaired by telomerase, a reverse transcriptase that adds hexanucleotides to the 3' end of the DNA leading strand. In humans, germline mutations in telomere-biol…
| 2 / 2 | Completed scholarships in Brazil |
| 1 / 1 | Ongoing scholarships abroad |
| 3 / 3 | All Scholarships |
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