bachelor's at Ciencias Biológicas from Universidade Estadual Paulista Júlio de Mesquita Filho (1979), master's at Microbiology from Universidade Federal de São Paulo (1988) and doctorate at Microbiology from Universidade Federal de São Paulo (1995). Has experience in Immunology and Genetics, focusing on Immunohematology, acting on the following subjects: Genetics of blood groups, Complexities of Rh System, Complex cases in Immunohematology, Blood group antigens expression, Rare blood groups, Clinical and laboratory applications of blood group antigens and antibodies, Red blood cell alloimmunization, Blood groups and diseases (Source: Lattes Curriculum)
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Sickle Cell Anemia is the most prevalent hereditary disease in Brazil, affecting approximately 30,000 Brazilians. The main therapy used to prevent and treat the acute and chronic complications associated with sickle cell disease is the transfusion of packed red blood cells. However, the occurrence of antibodies against transfused red blood cells is one of the serious complications of tran…
Permanent migration among the inhabitants of Brazil and Argentina has a direct impact on public health. In the group of patients who currently seek transfusion medicine services in Brazil, we have observed specific red blood cell phenotype and genotypes from Argentine population and vice versa. This variability is responsible, on some occasions, for alloimmunizationevents and reduction of…
Patients with sickle cell anemia are among one of transfused populations more often alloimmunized to red blood cell (RBC) antigens. With a better understanding of the genetic factors that predispose RBC alloimmunization, it will be possible to devise strategies of blood transfusions that will reduce the risk of alloimmunization and adverse reactions to transfusion. The molecular analysis …
(Only some records are available in English at this moment)
Patients with sickle cell anemia are among one of the most frequently transfused population alloimmunized, probably due to differences in polymorphic immunogenic erythrocyte antigens between blood donors, who are caucasians in general, and predominantly African descent patients. A better understanding of genes that may be associated with erythrocyte alloimmunization can elucidate new stra…
Blood transfusion is a vital therapy in treating and preventing the complications of sickle cell disease (SCD). However, despite transfusions of packed red blood cells significantly improve morbidity and mortality in this patient population, their use is complicated by the high incidence of alloimmunization, a serious complication in patients with SCD can result in Delayed Hemolytic Trans…
The knowledge of blood group antigens is essential to transfusional practice, because antibodies against those antigens can be a major problem in the clinic, mainly in the cases of patients with hemoglobinopathies or others diseases that require blood transfusions. Blood group genotyping can contribute significantly in the quality of the phenotyped transfused blood, especially in multi-tr…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 12 / 9 | Completed research grants |
| 8 / 5 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 22 / 15 | All research grants and scholarships |
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CV Lattes
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