CV Lattes
Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Ana Carolina de Avelar Muraca in research grants and scholarships supported by FAPESP.
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Benzyne chemistry has found applications in organic chemistry, including total syntheses of natural products and preparations of functional materials. In this sense, 2-(trimethylsilyl)aryl trifluoromethanesulfonates appear as an important alternative for the formation of benzyne and derivatives under mild reaction conditions. Accordingly, we intend to develop alternative routes for the sy…
Due to the considerable importance of 2-(trimethylsilyl)aryl triflates in the current context of the benzyne chemistry, we intend to develop the convergent total synthesis of the aporphine alkaloid (R)-(-)-apomorphine, which is used as medicine in the therapy of Parkinson's disease and in the treatment of erectile dysfunction, employing approach that presents in the key step [4+2] cycload…
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