Abstract
Acute kidney injury (AKI) is characterized by an abrupt reduction in glomerular filtration and an increase in plasma creatinine values to 1.5 to 2 times the baseline value or an increase of 0.3 mg / dl or reduced urinary flow 0.5 ml / kg / h within 6 hours. Objective: To evaluate the effect of treatment with polymyxin B sulfate in models of risk factors for diabetes mellitus and renal isc…