Abstract
Bisphosphonates (BPs) are a class of drugs used in the treatment of some bone diseases or osteotropic malignancies. BPs exert potent inhibitory effect on bone resorption. Among the adverse effects is the occurrence of Bisphosphonate-Related Osteonecrosis of the Jaws (BRONJ). The pathogenesis of the disease is poorly understood, which hinders its prevention and treatment. Among the risk fa…